Prostaglandin E(2), a postulated astrocyte-derived neurovascular coupling agent, constricts rather than dilates parenchymal arterioles

It has been proposed that prostaglandin E(2) (PGE(2)) is released from astrocytic endfeet to dilate parenchymal arterioles through activation of prostanoid (EP(4)) receptors during neurovascular coupling. However, the direct effects of PGE(2) on isolated parenchymal arterioles have not been tested....

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Bibliografiske detaljer
Main Authors: Dabertrand, Fabrice, Hannah, Rachael M, Pearson, Jessica M, Hill-Eubanks, David C, Brayden, Joseph E, Nelson, Mark T
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Brief Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618402/
https://ncbi.nlm.nih.gov/pubmed/23385200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.9
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