Prostaglandin E(2), a postulated astrocyte-derived neurovascular coupling agent, constricts rather than dilates parenchymal arterioles

It has been proposed that prostaglandin E(2) (PGE(2)) is released from astrocytic endfeet to dilate parenchymal arterioles through activation of prostanoid (EP(4)) receptors during neurovascular coupling. However, the direct effects of PGE(2) on isolated parenchymal arterioles have not been tested....

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Dades bibliogràfiques
Autors principals: Dabertrand, Fabrice, Hannah, Rachael M, Pearson, Jessica M, Hill-Eubanks, David C, Brayden, Joseph E, Nelson, Mark T
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
Matèries:
Brief Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618402/
https://ncbi.nlm.nih.gov/pubmed/23385200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.9
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