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Identification of a cell retention signal in the B-chain of platelet-derived growth factor and in the long splice version of the A-chain.

The B-chain homodimer of platelet-derived growth factor (PDGF) is only very inefficiently secreted and remains largely associated with the producer cell; in contrast, the dimer of the short, and most common, splice variant of the A-chain is secreted. To identify the structural background to the diff...

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Detalhes bibliográficos
Main Authors: Ostman, A, Andersson, M, Betsholtz, C, Westermark, B, Heldin, C H
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC361840/
https://ncbi.nlm.nih.gov/pubmed/1782212
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