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Detection of Ancestry Informative HLA Alleles Confirms the Admixed Origins of Japanese Population

The polymorphisms in the human leukocyte antigen (HLA) region are powerful tool for studying human evolutionary processes. We investigated genetic structure of Japanese by using five-locus HLA genotypes (HLA-A, -B, -C, -DRB1, and -DPB1) of 2,005 individuals from 10 regions of Japan. We found a signi...

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Detalhes bibliográficos
Main Authors: Nakaoka, Hirofumi, Mitsunaga, Shigeki, Hosomichi, Kazuyoshi, Shyh-Yuh, Liou, Sawamoto, Taiji, Fujiwara, Tsutomu, Tsutsui, Naohisa, Suematsu, Koji, Shinagawa, Akira, Inoko, Hidetoshi, Inoue, Ituro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618337/
https://ncbi.nlm.nih.gov/pubmed/23577161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060793
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