The transactivating domain of the c-Jun proto-oncoprotein is required for cotransformation of rat embryo cells.

The nuclear phosphoprotein c-Jun, encoded by the proto-oncogene c-jun, is a major component of the AP-1 complex. A potent transcriptional regulator, c-jun is also able to transform normal rat embryo cells in cooperation with an activated c-Ha-ras gene. By deletion analysis, we identified the regions...

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Udgivet i:Mol Cell Biol
Main Authors: Alani, R, Brown, P, Binétruy, B, Dosaka, H, Rosenberg, R K, Angel, P, Karin, M, Birrer, M J
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361817/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1944289/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.12.6286
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