The transactivating domain of the c-Jun proto-oncoprotein is required for cotransformation of rat embryo cells.

The nuclear phosphoprotein c-Jun, encoded by the proto-oncogene c-jun, is a major component of the AP-1 complex. A potent transcriptional regulator, c-jun is also able to transform normal rat embryo cells in cooperation with an activated c-Ha-ras gene. By deletion analysis, we identified the regions...

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Main Authors: Alani, R, Brown, P, Binétruy, B, Dosaka, H, Rosenberg, R K, Angel, P, Karin, M, Birrer, M J
Format: Artigo
Jezik:Inglês
Izdano: 1991
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC361817/
https://ncbi.nlm.nih.gov/pubmed/1944289
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