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Naturally occurring HCA1 missense mutations result in loss of function: potential impact on lipid deposition

The hydroxy-carboxylic acid receptor (HCA1) is a G protein-coupled receptor that is highly expressed on adipocytes and considered a potential target for the treatment of dyslipidemia. In the current study, we investigated the pharmacological properties of naturally occurring variants in this recepto...

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Autors principals: Doyle, Jamie R., Lane, Jacqueline M., Beinborn, Martin, Kopin, Alan S.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617956/
https://ncbi.nlm.nih.gov/pubmed/23268337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M034660
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