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A human alpha-fetoprotein enhancer-binding protein, ATBF1, contains four homeodomains and seventeen zinc fingers.

We have isolated a full-length cDNA encoding a protein (ATBF1) that binds to an AT-rich motif in the human alpha-fetoprotein gene enhancer. The amino acid sequence deduced from the cDNA revealed that this is the largest DNA-binding protein (306 kDa) known to date, containing four homeodomains, 17 zi...

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Publicat a:Mol Cell Biol
Autors principals: Morinaga, T, Yasuda, H, Hashimoto, T, Higashio, K, Tamaoki, T
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361769/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1719379/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.12.6041-6049.1991
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