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Comparative Studies of Disordered Proteins with Similar Sequences: Application to Aβ40 and Aβ42
Quantitative comparisons of intrinsically disordered proteins (IDPs) with similar sequences, such as mutant forms of the same protein, may provide insights into IDP aggregation—a process that plays a role in several neurodegenerative disorders. Here we describe an approach for modeling IDPs with sim...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Biophysical Society
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3617440/ https://ncbi.nlm.nih.gov/pubmed/23561531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.02.023 |
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