Comparative Studies of Disordered Proteins with Similar Sequences: Application to Aβ40 and Aβ42

Quantitative comparisons of intrinsically disordered proteins (IDPs) with similar sequences, such as mutant forms of the same protein, may provide insights into IDP aggregation—a process that plays a role in several neurodegenerative disorders. Here we describe an approach for modeling IDPs with sim...

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Bibliographic Details
Main Authors: Fisher, Charles K., Ullman, Orly, Stultz, Collin M.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2013
Subjects:
Proteins and Nucleic Acids
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617440/
https://ncbi.nlm.nih.gov/pubmed/23561531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.02.023
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