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A Periodic Pattern of Evolutionarily Conserved Basic and Acidic Residues Constitutes the Binding Interface of Actin-Tropomyosin

Actin filament cytoskeletal and muscle functions are regulated by actin binding proteins using a variety of mechanisms. A universal actin filament regulator is the protein tropomyosin, which binds end-to-end along the length of the filament. The actin-tropomyosin filament structure is unknown, but t...

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Detalhes bibliográficos
Main Authors: Barua, Bipasha, Fagnant, Patricia M., Winkelmann, Donald A., Trybus, Kathleen M., Hitchcock-DeGregori, Sarah E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617264/
https://ncbi.nlm.nih.gov/pubmed/23420843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.451161
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