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Evolutionarily conserved surface residues constitute actin binding sites of tropomyosin
Tropomyosin (Tm) is a two-chained, α-helical coiled-coil protein that associates end-to-end to form a continuous strand along actin filaments and regulates the functions and stability of actin in eukaryotic muscle and nonmuscle cells. Mutations in Tm cause skeletal and cardiac myopathies. We applied...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3121822/ https://ncbi.nlm.nih.gov/pubmed/21642532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101221108 |
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