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Evolutionarily conserved surface residues constitute actin binding sites of tropomyosin

Tropomyosin (Tm) is a two-chained, α-helical coiled-coil protein that associates end-to-end to form a continuous strand along actin filaments and regulates the functions and stability of actin in eukaryotic muscle and nonmuscle cells. Mutations in Tm cause skeletal and cardiac myopathies. We applied...

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Bibliografische gegevens
Hoofdauteurs: Barua, Bipasha, Pamula, Melissa C., Hitchcock-DeGregori, Sarah E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121822/
https://ncbi.nlm.nih.gov/pubmed/21642532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101221108
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