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Nutrient transporters: the Achilles' heel of anabolism

Highly proliferative cells, including cancer cells, require a constant supply of molecular building blocks to support their growth. To acquire substrates such as glucose and amino acids from the extracellular space, dividing cells rely on transporter proteins in the plasma membrane. Numerous studies...

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Autores principales: McCracken, Alison N., Edinger, Aimee L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617053/
https://ncbi.nlm.nih.gov/pubmed/23402769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2013.01.002
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