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Acidic/IQ Motif Regulator of Calmodulin()

The small IQ motif proteins PEP-19 (62 amino acids) and RC3 (78 amino acids) greatly accelerate the rates of Ca(2+) binding to sites III and IV in the C-domain of calmodulin (CaM). We show here that PEP-19 decreases the degree of cooperativity of Ca(2+) binding to sites III and IV, and we present a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Putkey, John A., Waxham, M. Neal, Gaertner, Tara R., Brewer, Kari J., Goldsmith, Michael, Kubota, Yoshihisa, Kleerekoper, Quinn K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617039/
https://ncbi.nlm.nih.gov/pubmed/17991744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M703831200
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