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Regulation of IMP dehydrogenase gene expression by its end products, guanine nucleotides.

To study the regulation of IMP dehydrogenase (IMPDH), the rate-limiting enzyme of guanine nucleotide biosynthesis, we examined the effects of nucleosides, nucleotides, nucleotide analogs, or the IMPDH inhibitor mycophenolic acid (MPA) on the steady-state levels of IMPDH mRNA. The results indicated t...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Glesne, D A, Collart, F R, Huberman, E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1991
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361678/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1717828/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.11.5417-5425.1991
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