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A unified procedure for meta-analytic evaluation of surrogate end points in randomized clinical trials

The meta-analytic approach to evaluating surrogate end points assesses the predictiveness of treatment effect on the surrogate toward treatment effect on the clinical end point based on multiple clinical trials. Definition and estimation of the correlation of treatment effects were developed in line...

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Detalhes bibliográficos
Main Authors: Dai, James Y., Hughes, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616754/
https://ncbi.nlm.nih.gov/pubmed/22394448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxs003
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