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Statistical controversies in clinical research: an initial evaluation of a surrogate end point using a single randomized clinical trial and the Prentice criteria

Surrogate end point research has grown in recent years with the increasing development and usage of biomarkers in clinical research. Surrogacy analysis is derived through randomized clinical trial data and it is carried out at the individual level and at the trial level. A common surrogate analysis...

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Pubblicato in:Ann Oncol
Autore principale: Heller, G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692987/
https://ncbi.nlm.nih.gov/pubmed/26254442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdv333
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