Prolonged survival and delayed progression of pancreatic intraepithelial neoplasia in LSL-Kras(G12D/+);Pdx-1-Cre mice by vitamin E δ-tocotrienol

The highly lethal nature of pancreatic cancer and the increasing recognition of high-risk individuals have made research into chemoprevention a high priority. Here, we tested the chemopreventive activity of δ-tocotrienol, a bioactive vitamin E derivative extracted from palm fruit, in the LSL-Kras(G1...

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Autori principali: Husain, Kazim, Centeno, Barbara A., Chen, Dung-Tsa, Fulp, William J., Perez, Marta, Zhang Lee, Guo, Luetteke, Noreen, Hingorani, Sunil R., Sebti, Said M., Malafa, Mokenge P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616675/
https://ncbi.nlm.nih.gov/pubmed/23302291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt002
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