Enhanced Intrapulmonary Delivery of Anticancer siRNA for Lung Cancer Therapy Using Cationic Ethylphosphocholine-based Nanolipoplexes

Here, we report a cationic nanolipoplex as a pulmonary cellular delivery system for small-interfering RNA (siRNA). Six nanoliposomes differing in cationic lipids were formulated and screened in vitro and in vivo for cellular delivery functions in lung cells/tissues. Although the six nanoliposomes sh...

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Detalhes bibliográficos
Main Authors: Shim, Gayong, Choi, Hyun-woo, Lee, Sangbin, Choi, Junhyeok, Yu, Yong Hee, Park, Da-Eui, Choi, Yongseok, Kim, Chan-Wha, Oh, Yu-Kyoung
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616525/
https://ncbi.nlm.nih.gov/pubmed/23380818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.10
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