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Fine-tuning BMP7 signalling in adipogenesis by UBE2O/E2-230K-mediated monoubiquitination of SMAD6

SMAD6 is a crucial feedback inhibitory regulator of bone morphogenetic protein (BMP)/SMAD signalling. Although little is known regarding the post-transcriptional modification of inhibitory SMADs and the mechanism by which their function is regulated. In this study, using a whole proteomic interactio...

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Detalhes bibliográficos
Main Authors: Zhang, Xiaofei, Zhang, Juan, Bauer, Andreas, Zhang, Long, Selinger, Douglas W, Lu, Chris X, ten Dijke, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616286/
https://ncbi.nlm.nih.gov/pubmed/23455153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.38
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