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Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm
How regulatory information is encoded in the genome is poorly understood and poses a challenge when studying biological processes. We demonstrate here that genomic redistribution of Oct4 by alternative partnering with Sox2 and Sox17 is a fundamental regulatory event of endodermal specification. We s...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
European Molecular Biology Organization
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3616284/ https://ncbi.nlm.nih.gov/pubmed/23474895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.31 |
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