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Dynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunit

Dynactin is a protein complex required for the in vivo function of cytoplasmic dynein, a microtubule (MT)-based motor. Dynactin binds both dynein and MTs via its p150(Glued) subunit, but little is known about the ‘pointed-end complex’ that includes the protein subunits Arp11, p62 and the p27/p25 het...

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Bibliografiske detaljer
Main Authors: Yeh, Ting-Yu, Kowalska, Anna K, Scipioni, Brett R, Cheong, Frances Ka Yan, Zheng, Meiying, Derewenda, Urszula, Derewenda, Zygmunt S, Schroer, Trina A
Format: Artigo
Sprog:Inglês
Udgivet: European Molecular Biology Organization 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616283/
https://ncbi.nlm.nih.gov/pubmed/23455152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.30
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