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Dynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunit
Dynactin is a protein complex required for the in vivo function of cytoplasmic dynein, a microtubule (MT)-based motor. Dynactin binds both dynein and MTs via its p150(Glued) subunit, but little is known about the ‘pointed-end complex’ that includes the protein subunits Arp11, p62 and the p27/p25 het...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
European Molecular Biology Organization
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3616283/ https://ncbi.nlm.nih.gov/pubmed/23455152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.30 |
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