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NAD(+) as a signaling molecule modulating metabolism

The ability of NAD(+) to act as a metabolic cofactor and as a rate-limiting cosubstrate for many enzymes, particularly the sirtuins, has led to the identification of a pivotal role of NAD(+) levels in the control of whole body metabolic homeostasis. Bioavailability and compartmentalization of NAD(+)...

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Detalhes bibliográficos
Main Authors: Cantó, Carles, Auwerx, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616234/
https://ncbi.nlm.nih.gov/pubmed/22345172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/sqb.2012.76.010439
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