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Crystal Structure of KLHL3 in Complex with Cullin3
KLHL3 is a BTB-BACK-Kelch family protein that serves as a substrate adapter in Cullin3 (Cul3) E3 ubiquitin ligase complexes. KLHL3 is highly expressed in distal nephron tubules where it is involved in the regulation of electrolyte homeostasis and blood pressure. Mutations in KLHL3 have been identifi...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2013
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3616122/ https://ncbi.nlm.nih.gov/pubmed/23573258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060445 |
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