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Cdc6: A multi-functional molecular switch with critical role in carcinogenesis

Research in the last decade revealed an additional role for the Replication Licensing Factor Cdc6 in transcriptional regulation. This novel function has been linked to human cancer development. Here, we summarize all the findings arguing over a role of Cdc6 as a transcriptional repressor and shed li...

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Detalhes bibliográficos
Main Authors: Petrakis, Thodoris G., Vougas, Konstantinos, Gorgoulis, Vassilis G.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616082/
https://ncbi.nlm.nih.gov/pubmed/22771947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.20301
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