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Cdc42 is an antihypertrophic molecular switch in the mouse heart

To improve contractile function, the myocardium undergoes hypertrophic growth without myocyte proliferation in response to both pathologic and physiologic stimulation. Various membrane-bound receptors and intermediate signal transduction pathways regulate the induction of cardiac hypertrophy, but th...

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Detalhes bibliográficos
Main Authors: Maillet, Marjorie, Lynch, Jeffrey M., Sanna, Bastiano, York, Allen J., Zheng, Yi, Molkentin, Jeffery D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752064/
https://ncbi.nlm.nih.gov/pubmed/19741299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37694
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