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Oral bioavailability of cantharidin-loaded solid lipid nanoparticles

BACKGROUND: The clinical application of cantharidin (CA) is limited by its insolubility, toxicity and short half-life in circulation. This study aims to achieve a steady and sustained blood concentration–time profile, using solid lipid nanoparticles (SLNs) as a drug carrier. METHODS: CA-SLNs were pr...

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Detalhes bibliográficos
Main Authors: Dang, Yun-Jie, Zhu, Chun-Yan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615953/
https://ncbi.nlm.nih.gov/pubmed/23298453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8546-8-1
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