Effect of verapamil on systemic exposure and safety of umeclidinium and vilanterol: a randomized and open-label study

BACKGROUND: The combination of umeclidinium (UMEC), a long-acting muscarinic receptor antagonist, and vilanterol (VI), a selective long-acting β(2) agonist, is in development for the treatment of chronic obstructive pulmonary disease (COPD). This study evaluated the pharmacokinetics, safety and tole...

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Bibliografiset tiedot
Päätekijät: Mehta, Rashmi, Kelleher, Dennis, Preece, Andrew, Hughes, Stephen, Crater, Glenn
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Dove Medical Press 2013
Aiheet:
Original Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615930/
https://ncbi.nlm.nih.gov/pubmed/23569370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S40859
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