Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of Umeclidinium and Vilanterol Alone and in Combination: A Randomized Crossover Trial

Umeclidinium bromide (GSK573719; UMEC), a new long-acting muscarinic receptor antagonist (LAMA), is in development with vilanterol (GW642444; VI), a selective long-acting β(2) agonist (LABA), as a once-daily inhaled combination therapy for the treatment of chronic obstructive pulmonary disease (COPD...

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Detalhes bibliográficos
Main Authors: Kelleher, Dennis L., Mehta, Rashmi S., Jean-Francois, Bernadette M., Preece, Andrew F., Blowers, James, Crater, Glenn D., Thomas, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524248/
https://ncbi.nlm.nih.gov/pubmed/23284643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050716
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