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Epigenetic therapy: use of agents targeting deacetylation and methylation in cancer management
The emergence of epigenetic mechanisms as key regulators of gene expression has led to dramatic advances in understanding cancer biology. Driven by complex layers that include aberrant DNA methylation and histone modification, epigenetic aberrations have emerged as critical processes that disrupt ce...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Dove Medical Press
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3615839/ https://ncbi.nlm.nih.gov/pubmed/23569385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S34680 |
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