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Epigenetic therapy: use of agents targeting deacetylation and methylation in cancer management

The emergence of epigenetic mechanisms as key regulators of gene expression has led to dramatic advances in understanding cancer biology. Driven by complex layers that include aberrant DNA methylation and histone modification, epigenetic aberrations have emerged as critical processes that disrupt ce...

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Dettagli Bibliografici
Autori principali: Ho, Allen S, Turcan, Sevin, Chan, Timothy A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615839/
https://ncbi.nlm.nih.gov/pubmed/23569385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S34680
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