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Synthesis and σ(1) Receptor Binding of Halogenated N,N′-Diphenethylethylenediamines

Eight halogenated N,N′-diphenethylethylenediamines were synthesized, characterized and evaluated for σ(1) receptor binding affinity in vitro. Measurements of lipophilicity also were obtained. The substitution pattern on one of the aromatic rings remained constant as 3,4-dichloro, while the substitue...

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Main Authors: Fitzsimmons, Jonathan M., Lever, John R., Lever, Susan Z.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615439/
https://ncbi.nlm.nih.gov/pubmed/23565348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2161-0444.1000102
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