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Heparin inhibits c-fos and c-myc mRNA expression in vascular smooth muscle cells.

Heparin is a potent inhibitor of vascular smooth muscle cell (VSMC) growth. In this paper we show that heparin suppressed the induction of c-fos and c-myc mRNA in rat and calf VSMC. This effect of heparin is closely associated with its growth-inhibitory activity, as shown by isolating and characteri...

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Detalhes bibliográficos
Main Authors: Pukac, L A, Castellot, J J, Wright, T C, Caleb, B L, Karnovsky, M J
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC361524/
https://ncbi.nlm.nih.gov/pubmed/2099192
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