Heparin suppresses the induction of c-fos and c-myc mRNA in murine fibroblasts by selective inhibition of a protein kinase C-dependent pathway.

Heparin is a complex glycosaminoglycan that inhibits the proliferation of several cell types in culture and in vivo. To begin to define the mechanism(s) by which heparin exerts its antiproliferative effects, we asked whether heparin interferes with the expression of the growth factor-inducible proto...

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Autori principali: Wright, T C, Pukac, L A, Castellot, J J, Karnovsky, M J, Levine, R A, Kim-Park, H Y, Campisi, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1989
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC287094/
https://ncbi.nlm.nih.gov/pubmed/2541434
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