Heparin suppresses the induction of c-fos and c-myc mRNA in murine fibroblasts by selective inhibition of a protein kinase C-dependent pathway.

Heparin is a complex glycosaminoglycan that inhibits the proliferation of several cell types in culture and in vivo. To begin to define the mechanism(s) by which heparin exerts its antiproliferative effects, we asked whether heparin interferes with the expression of the growth factor-inducible proto...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Wright, T C, Pukac, L A, Castellot, J J, Karnovsky, M J, Levine, R A, Kim-Park, H Y, Campisi, J
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1989
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287094/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2541434/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.9.3199
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