A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1.

Phospholipase C-gamma (PLC-gamma) is a substrate of the fibroblast growth factor receptor (FGFR; encoded by the flg gene) and other receptors with tyrosine kinase activity. It has been demonstrated that the src homology region 2 (SH2 domain) of PLC-gamma and of other signalling molecules such as GTP...

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Bibliographic Details
Main Authors: Mohammadi, M, Honegger, A M, Rotin, D, Fischer, R, Bellot, F, Li, W, Dionne, C A, Jaye, M, Rubinstein, M, Schlessinger, J
Format: Artigo
Language:Inglês
Published: 1991
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC361508/
https://ncbi.nlm.nih.gov/pubmed/1656221
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