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A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1.

Phospholipase C-gamma (PLC-gamma) is a substrate of the fibroblast growth factor receptor (FGFR; encoded by the flg gene) and other receptors with tyrosine kinase activity. It has been demonstrated that the src homology region 2 (SH2 domain) of PLC-gamma and of other signalling molecules such as GTP...

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Publicat a:Mol Cell Biol
Autors principals: Mohammadi, M, Honegger, A M, Rotin, D, Fischer, R, Bellot, F, Li, W, Dionne, C A, Jaye, M, Rubinstein, M, Schlessinger, J
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361508/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1656221/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.10.5068-5078.1991
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