Shift Work or Food Intake during the Rest Phase Promotes Metabolic Disruption and Desynchrony of Liver Genes in Male Rats

In the liver, clock genes are proposed to drive metabolic rhythms. These gene rhythms are driven by the suprachiasmatic nucleus (SCN) mainly by food intake and via autonomic and hormonal pathways. Forced activity during the normal rest phase, induces also food intake, thus neglecting the signals of...

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Main Authors: Salgado-Delgado, Roberto C., Saderi, Nadia, Basualdo, María del Carmen, Guerrero-Vargas, Natali N., Escobar, Carolina, Buijs, Ruud M.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615006/
https://ncbi.nlm.nih.gov/pubmed/23565183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060052
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