Circadian disruption promotes tumor growth by anabolic host metabolism; experimental evidence in a rat model

Abstract Background Light at night creates a conflicting signal to the biological clock and disrupts circadian physiology. In rodents, light at night increases the risk to develop mood disorders, overweight, disrupted energy metabolism, immune dysfunction and cancer. We hypothesized that constant li...

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Detalhes bibliográficos
Main Authors: Natalí N. Guerrero-Vargas, Raful Navarro-Espíndola, Mara A. Guzmán-Ruíz, María del Carmen Basualdo, Estefania Espitia-Bautista, Ana López-Bago, Ricardo Lascurain, Cinthya Córdoba-Manilla, Ruud M. Buijs, Carolina Escobar
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-09-01
Colecção:BMC Cancer
Assuntos:
Light at night
Circadian disruption
Tumor development
Inflammation
Metabolism and obesity
Acesso em linha:http://link.springer.com/article/10.1186/s12885-017-3636-3
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