Gα(o) potentiates estrogen receptor α activity via the ERK signaling pathway

The estrogen receptor α (ERα) is a transcription factor that mediates the biological effects of 17β-estradiol (E(2)). ERα transcriptional activity is also regulated by cytoplasmic signaling cascades. Here, several Gα protein subunits were tested for their ability to regulate ERα activity. Reporter a...

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Detalhes bibliográficos
Main Authors: Bratton, Melyssa R, Antoon, James W, Duong, Bich N, Frigo, Daniel E, Tilghman, Syreeta, Collins-Burow, Bridgette M, Elliott, Steven, Tang, Yan, Melnik, Lilia I, Lai, Ling, Alam, Jawed, Beckman, Barbara S, Hill, Steven M, Rowan, Brian G, McLachlan, John A, Burow, Matthew E
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614348/
https://ncbi.nlm.nih.gov/pubmed/22562654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-12-0097
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