Antiestrogenic Activity of Flavonoid Phytochemicals Mediated via the c-Jun N-terminal Protein Kinase Pathway: Cell-type specific regulation of estrogen receptor alpha

Flavonoid phytochemicals act as both agonists and antagonists of the human estrogen receptors (ERs). While a number of these compounds act by directly binding to the ER, certain phytochemicals, such as the flavonoid compounds chalcone and flavone, elicit antagonistic effects on estrogen signaling in...

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Autori principali: Collins-Burow, Bridgette M., Antoon, James W., Frigo, Daniel E., Elliott, Steven, Weldon, Christopher B., Boue, Stephen M., Beckman, Barbara S., Curiel, Tyler J., Alam, Jawed, McLachlan, John A., Burow, Matthew E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083692/
https://ncbi.nlm.nih.gov/pubmed/22634477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2012.05.004
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