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An LC-MS/MS Assay for Detection and Quantification of the Dipeptide Gly-Gln in Rat Brain

The enzymatic cleavage products of β-endorphin (β-endorphin(1-27) and Gly-Gln) reduce voluntary alcohol consumption in alcohol preferring P rats. Gly-Gln also inhibits the reward benefiting effects of morphine and nicotine. It would be useful for the investigation of this effect to have an analytica...

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Hlavní autoři: Bobba, Sudheer, Resch, Garth E., Gutheila, William G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613996/
https://ncbi.nlm.nih.gov/pubmed/22446498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2012.03.007
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