STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients

Myeloid-derived suppressor cells (MDSC) play a key immunosuppressive role in various types of cancer, including head and neck squamous cell carcinoma (HNSCC). In this study, we characterized CD14(+)HLA-DR(–/lo) cells sorted from the tumors, draining lymph nodes, and peripheral blood of HNSCC patient...

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Bibliographische Detailangaben
Hauptverfasser: Vasquez-Dunddel, David, Pan, Fan, Zeng, Qi, Gorbounov, Mikhail, Albesiano, Emilia, Fu, Juan, Blosser, Richard L., Tam, Ada J., Bruno, Tullia, Zhang, Hao, Pardoll, Drew, Kim, Young
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613901/
https://ncbi.nlm.nih.gov/pubmed/23454751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60083
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