Targeted oxidation of Torpedo californica acetylcholinesterase by singlet oxygen: Identification of N-formylkynurenine tryptophan derivatives within the active-site gorge of its complex with the photosensitizer methylene blue

The principal role of acetylcholinesterase (AChE) is termination of impulse transmission at cholinergic synapses by rapid hydrolysis of the neurotransmitter acetylcholine. The active site of AChE is near the bottom of a long and narrow gorge lined with aromatic residues. It contains a catalytic ‘ani...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Triquigneaux, Mathilde M., Ehrenshaft, Marilyn, Roth, Esther, Silman, Israel, Ashani, Yakov, Mason, Ronald P., Weiner, Lev, Deterding, Leesa J.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613852/
https://ncbi.nlm.nih.gov/pubmed/22888904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20120992
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars