Minocycline selectively inhibits M1 polarization of microglia

Minocycline is commonly used to inhibit microglial activation. It is widely accepted that activated microglia exert dual functions, that is, pro-inflammatory (M1) and anti-inflammatory (M2) functions. The in vivo status of activated microglia is probably on a continuum between these two extreme stat...

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Autors principals: Kobayashi, K, Imagama, S, Ohgomori, T, Hirano, K, Uchimura, K, Sakamoto, K, Hirakawa, A, Takeuchi, H, Suzumura, A, Ishiguro, N, Kadomatsu, K
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613832/
https://ncbi.nlm.nih.gov/pubmed/23470532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.54
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