Minocycline Prevents Osmotic Demyelination Syndrome by Inhibiting the Activation of Microglia

Rapid correction of chronic hyponatremia can lead to osmotic demyelination syndrome (ODS), a severe demyelination disease. The microglia that accumulate in the demyelinative lesions may play a detrimental role in the pathogenesis of ODS by producing proinflammatory cytokines, suggesting that they ma...

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Bibliografiske detaljer
Main Authors: Suzuki, Haruyuki, Sugimura, Yoshihisa, Iwama, Shintaro, Suzuki, Hiromi, Nobuaki, Ozaki, Nagasaki, Hiroshi, Arima, Hiroshi, Sawada, Makoto, Oiso, Yutaka
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2010
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014022/
https://ncbi.nlm.nih.gov/pubmed/21030598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010040438
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