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Minocycline Prevents Osmotic Demyelination Syndrome by Inhibiting the Activation of Microglia
Rapid correction of chronic hyponatremia can lead to osmotic demyelination syndrome (ODS), a severe demyelination disease. The microglia that accumulate in the demyelinative lesions may play a detrimental role in the pathogenesis of ODS by producing proinflammatory cytokines, suggesting that they ma...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Nephrology
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3014022/ https://ncbi.nlm.nih.gov/pubmed/21030598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010040438 |
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