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Minocycline modulates microglia polarization in ischemia-reperfusion model of retinal degeneration and induces neuroprotection

Retinal ischemia-reperfusion (IR) injury causes irreversible loss of neurons and ultimately leads to permanent visual impairment and blindness. The cellular response under this pathological retinal condition is less clear. Using genetically modified mice, we systematically examined the behavior of m...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Ahmed, Amel, Wang, Lei-Lei, Abdelmaksoud, Safaa, Aboelgheit, Amal, Saeed, Safaa, Zhang, Chun-Li
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656679/
https://ncbi.nlm.nih.gov/pubmed/29070819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14450-5
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