Minocycline modulates microglia polarization in ischemia-reperfusion model of retinal degeneration and induces neuroprotection

Retinal ischemia-reperfusion (IR) injury causes irreversible loss of neurons and ultimately leads to permanent visual impairment and blindness. The cellular response under this pathological retinal condition is less clear. Using genetically modified mice, we systematically examined the behavior of m...

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Udgivet i:Sci Rep
Main Authors: Ahmed, Amel, Wang, Lei-Lei, Abdelmaksoud, Safaa, Aboelgheit, Amal, Saeed, Safaa, Zhang, Chun-Li
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656679/
https://ncbi.nlm.nih.gov/pubmed/29070819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14450-5
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