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RNA-seq–based mapping and candidate identification of mutations from forward genetic screens

Forward genetic screens have elucidated molecular pathways required for innumerable aspects of life; however, identifying the causal mutations from such screens has long been the bottleneck in the process, particularly in vertebrates. We have developed an RNA-seq–based approach that identifies both...

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Detalhes bibliográficos
Main Authors: Miller, Adam C., Obholzer, Nikolaus D., Shah, Arish N., Megason, Sean G., Moens, Cecilia B.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613584/
https://ncbi.nlm.nih.gov/pubmed/23299976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.147322.112
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