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Identification of 33 candidate oncogenes by screening for base-specific mutations
BACKGROUND: Genes with recurrent codon-specific somatic mutations are likely drivers of tumorigenesis and potential therapeutic targets. Hypermutable cancers may represent a sensitive system for generation and selection of oncogenic mutations. METHODS: We utilised exome-sequencing data on 25 sporadi...
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Hlavní autoři: | , , , , , , , , , , , , , , , , , , , |
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Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
Nature Publishing Group
2014
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4200084/ https://ncbi.nlm.nih.gov/pubmed/25117815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.429 |
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